Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | SI | P14410 | 3/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28741367 | 0.74 | GUSB (0.37) | MGAMGAASIMGAM2GUSB | |
| SCHEMBL4627913 | 0.74 | MGAM (0.48) | MGAMGAASIMGAM2GUSB | |
| SCHEMBL27494914 | 0.74 | MMP1 (0.40) | MGAMGAASIMGAM2GUSB | |
| SCHEMBL27532210 | 0.73 | SNCA (0.41) | MGAMGAASIMGAM2GUSB | |
| SCHEMBL5239895 | 0.73 | HTR2A (0.48) | MGAMGAASIMGAM2GUSB | |
| SCHEMBL27493350 | 0.72 | RORC (0.41) | GUSBDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL20078269 | 0.70 | GUSB (0.50) | MGAMGAASIMGAM2GUSB | |
| SCHEMBL2075069 | 0.70 | SLC6A4 (0.67) | MGAMGAASIMGAM2GUSB | |
| SCHEMBL7364631 | 0.69 | GUSB (0.47) | MGAMGAASIMGAM2GUSB | |
| SCHEMBL10754767 | 0.68 | GAA (0.42) | MGAMGAASIMGAM2GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |