Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 2/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27557415 | 0.93 | GAA (0.40) | MMP1MMP2GAACYP1A2HSD17B10 | |
| SCHEMBL27495706 | 0.86 | LMNA (0.42) | MMP1MMP2GAACYP1A2HSD17B10 | |
| SCHEMBL28741367 | 0.85 | GUSB (0.37) | GAACYP1A2GUSBALDH1A1KMT2A | |
| SCHEMBL27495316 | 0.81 | TDO2 (0.42) | MMP1MMP2GAACYP1A2HSD17B10 | |
| SCHEMBL27493350 | 0.81 | RORC (0.41) | GUSBALDH1A1MAPT | |
| SCHEMBL27524768 | 0.78 | GUSB (0.37) | CYP1A2GUSBALDH1A1KMT2AMAPT | |
| SCHEMBL27510230 | 0.74 | THRB (0.40) | GUSBALDH1A1MAPT | |
| SCHEMBL27557417 | 0.74 | GAA (0.51) | GAACYP1A2HSD17B10NPC1RAB9A | |
| SCHEMBL28741365 | 0.74 | MGAM (0.41) | GAAGUSBALDH1A1KMT2AMGAM | |
| SCHEMBL28741340 | 0.72 | NPC1 (0.58) | GAACYP1A2HSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |