Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263014 | 0.87 | KDM4E (0.46) | KDM4EGLAGAAMAPTSMN1; SMN2 | |
| SCHEMBL5160393 | 0.81 | TBXAS1 (0.45) | KDM4EMAPTSMN1; SMN2RXFP1CYP4F2 | |
| SCHEMBL23219125 | 0.77 | TBXAS1 (0.45) | KDM4EGLAGAAMAPTSMN1; SMN2 | |
| SCHEMBL29852848 | 0.77 | TBXAS1 (0.45) | KDM4EGLAGAAMAPTSMN1; SMN2 | |
| SCHEMBL20592989 | 0.77 | PSD (0.36) | KDM4EGLAGAAMAPTSMN1; SMN2 | |
| SCHEMBL19697668 | 0.76 | PIK3CA (0.40) | KDM4EGLAGAAMAPTSMN1; SMN2 | |
| SCHEMBL1649636 | 0.76 | TGFBR1 (0.54) | KDM4EGLAGAAMAPTSMN1; SMN2 | |
| SCHEMBL20592991 | 0.76 | POLB (0.40) | KDM4EGAAMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL20592786 | 0.75 | RAB9A (0.40) | KDM4EGLAGAASMN1; SMN2RXFP1 | |
| SCHEMBL18786198 | 0.75 | POLB (0.44) | GAAPSDADORA2APIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450006-A | TrkB positive allosteric modulators | 斯特拉斯堡大学 | 2022-05-06 | — | — | CN | disclosed |