SCHEMBL2874282

SCHEMBL2874282

Cc1cc(O)cc(OC(CCC(=O)O)C(=O)O)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.40
PPARA Q07869 7/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
FFAR4 Q5NUL3 1/20 0.39
HCAR1 Q9BXC0 1/20 0.38
PTGES O14684 1/20 0.37
ALOX5 P09917 1/20 0.37
FOLH1 Q04609 2/20 0.35
POLB P06746 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2280554 0.73 SMN1; SMN2 (0.65) PPARGPPARASMN1; SMN2PTGESALOX5
SCHEMBL8527020 0.73 SMN1; SMN2 (0.60) PPARGPPARASMN1; SMN2PTGESALOX5
SCHEMBL5509034 0.73 PPARG (0.56) PPARGPPARA
SCHEMBL2276993 0.71 PPARG (0.40) PPARGPPARASMN1; SMN2PTGESALOX5
SCHEMBL4655017 0.71 PPARG (0.54) PPARGPPARASMN1; SMN2HCAR1PTGES
SCHEMBL2849301 0.70 VCAM1 (0.44) HCAR1ALDH1A1L3MBTL1
SCHEMBL11588663 0.69 PPARG (0.47) PPARGPPARA
Orcinol SCHEMBL2849303 0.68 HCAR1 (0.52) HCAR1ALDH1A1
SCHEMBL8521338 0.68 PPARG (0.52) PPARGPPARAFOLH1
SCHEMBL28969462 0.67 CYP1A2 (0.54) FOLH1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2150119-B1 DIHYDROXYBENZOATE POLYMERS AND USES THEREOF TYRX INC (US) 2018-04-11 EP disclosed
US-9491966-B2 Dihydroxybenzoate polymers and uses thereof TYRX, INC. (US) 2016-11-15 US disclosed
US-20100129417-A1 Dihydroxybenzoate Polymers and Uses Thereof MEDTRONIC, INC. 2010-05-27 US disclosed
EP-2150119-A1 DIHYDROXYBENZOATE POLYMERS AND USES THEREOF TYRX PHARMA INC. (US) 2010-02-10 EP disclosed
WO-2008137807-A1 DIHYDROXYBENZOATE POLYMERS AND USES THEREOF TYRX PHARMA, INC. (US) 2008-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100129417-A1 Dihydroxybenzoate Polymers and Uses Thereof DDT, QDPR, HPD PPARG 1338/4885PPARA 483/4885SMN1; SMN2 4832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.