Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833545 | 0.73 | GRM5 (0.53) | GRM5NOTUM | |
| SCHEMBL25581837 | 0.67 | GRM5 (0.62) | GRM5NOTUMDRD2DRD3 | |
| SCHEMBL8697197 | 0.67 | ICMT (0.60) | GRM5 | |
| SCHEMBL18622981 | 0.65 | KDM4E (0.53) | GRM5NOTUMDRD2DRD3NSD2 | |
| SCHEMBL7237232 | 0.65 | GRM5 (0.58) | GRM5NOTUMDRD2DRD3NSD2 | |
| SCHEMBL4629672 | 0.64 | GRM5 (1.00) | GRM5 | |
| SCHEMBL26847567 | 0.64 | NOTUM (0.49) | GRM5NOTUMDRD2DRD3NSD2 | |
| SCHEMBL30771644 | 0.64 | F11 (0.49) | GRM5 | |
| SCHEMBL7214056 | 0.64 | KDM4E (0.43) | GRM5NOTUMDRD2DRD3NSD2 | |
| SCHEMBL22515998 | 0.64 | ENPP3 (0.41) | GRM5NOTUMDRD2DRD3NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1246847-A | Nitrogen containing heteroaromatics as factor Xa inhibitors | DU PONT MERCK PHARMA (US) | 2000-03-08 | — | — | CN | disclosed |