SCHEMBL28745239

SCHEMBL28745239

Cc1ccc(C(=Cc2cccc(C)c2C)c2ccc(C)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.40
ATM Q13315 4/20 0.38
TRPA1 O75762 1/20 0.38
ALDH1A1 P00352 7/20 0.35
HTT P42858 3/20 0.35
LMNA P02545 3/20 0.35
PKM P14618 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HPGD P15428 1/20 0.35
NLRP1 Q9C000 1/20 0.35
NTSR1 P30989 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CES2 O00748 2/20 0.34
CES1 P23141 2/20 0.34
MAPT P10636 3/20 0.33
GAA P10253 1/20 0.33
RAB9A P51151 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10434287 0.80 PTGS2 (0.42) PTGS2ATMALDH1A1HTTLMNA
SCHEMBL5848427 0.76 PTGS2 (0.44) PTGS2ATMALDH1A1HTTLMNA
SCHEMBL9806295 0.72 ALDH1A1 (0.46) PTGS2ALDH1A1NPSR1HPGDTDP1
SCHEMBL5845628 0.71 TRPA1 (0.41) ATMTRPA1ALDH1A1SMN1; SMN2HPGD
SCHEMBL6548141 0.70 BRD4 (0.41) PTGS2ATMTRPA1ALDH1A1LMNA
SCHEMBL11805299 0.70 BRD4 (0.41) PTGS2ATMTRPA1ALDH1A1LMNA
P-Xylene SCHEMBL1959829 0.70 ACHE (0.53) ATMTRPA1ALDH1A1LMNASMN1; SMN2
Hydrochloric Acid SCHEMBL5143701 0.69 TRPA1 (0.40) ATMTRPA1ALDH1A1HTTLMNA
SCHEMBL879008 0.69 PTGS2 (0.49) PTGS2ALDH1A1LMNASMN1; SMN2MEN1
SCHEMBL2509405 0.69 PTGS2 (0.42) PTGS2ATMALDH1A1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1872946-A Organic light-emitting material and organic light-emitting element LAIBAO TECH CO LTD (CN) 2006-12-06 CN disclosed
CN-1268714-C Organic electroluminescent material and electroluminescent device RITDISPLAY CORP (CN) 2006-08-09 CN disclosed
CN-1504531-A Organic electroluminescent material and electroluminescent device 铼宝科技股份有限公司 2004-06-16 CN disclosed
CN-1504532-A Organic electroluminescent material and electroluminescent device 铼宝科技股份有限公司 2004-06-16 CN disclosed