SCHEMBL5848427

SCHEMBL5848427

Cc1ccc(C(=Cc2cc(C)c(C=C(c3ccc(C)cc3)c3ccc(C)cc3)cc2C)c2ccc(C)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.44
ALDH1A1 P00352 7/20 0.40
HTT P42858 3/20 0.40
NPSR1 Q6W5P4 3/20 0.40
LMNA P02545 3/20 0.40
HPGD P15428 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
PKM P14618 2/20 0.40
ATM Q13315 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NLRP1 Q9C000 1/20 0.40
MEN1 O00255 1/20 0.40
NTSR1 P30989 1/20 0.40
KMT2A Q03164 1/20 0.40
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6300153 0.77 CYP3A4 (0.38) PTGS2ALDH1A1LMNAHPGDTDP1
SCHEMBL6300151 0.77 CYP3A4 (0.38) PTGS2ALDH1A1LMNAHPGDTDP1
SCHEMBL28745239 0.76 PTGS2 (0.40) PTGS2ALDH1A1HTTNPSR1LMNA
SCHEMBL879008 0.75 PTGS2 (0.49) PTGS2ALDH1A1LMNAHPGDTDP1
SCHEMBL10434287 0.75 PTGS2 (0.42) PTGS2ALDH1A1HTTNPSR1LMNA
SCHEMBL8053369 0.75 PTGS2 (0.69) PTGS2ALDH1A1HTTNPSR1LMNA
SCHEMBL2925327 0.75 PTGS2 (0.69) PTGS2ALDH1A1HTTNPSR1LMNA
SCHEMBL9617925 0.74 ALDH1A1 (0.42) PTGS2ALDH1A1LMNATDP1PKM
SCHEMBL2509405 0.71 PTGS2 (0.42) PTGS2ALDH1A1HTTNPSR1LMNA
SCHEMBL8056495 0.71 PTGS2 (0.54) PTGS2ALDH1A1HTTNPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7029764-B2 Organic electroluminescent material and electroluminescent device by using the same RITDISPLAY CORPORATION (TW) 2006-04-18 US disclosed
US-7026061-B2 Organic electroluminescent material and organic electroluminescent element by using the same RITDISPLAY CORPORATION (TW) 2006-04-11 US disclosed
US-20060063034-A1 Organic electroluminescent material and organic electroluminescent device by using the same RITDISPLAY CORPORATION 2006-03-23 US disclosed
US-20040183432-A1 Organic electroluminescent material and organic electroluminescent element by using the same RIT DISPLAY CORPORATION (TW) 2004-09-23 US disclosed
US-20040146742-A1 Organic electroluminescent material and electroluminescent device by using the same RITDISPLAY CORPORATION (TW) 2004-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063034-A1 Organic electroluminescent material and organic electroluminescent device by using the same PIEZO1, L1CAM, OR10J3 PTGS2 2945/4885ALDH1A1 135/4885HTT 3029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.