Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2629425 | 0.80 | RAB9A (0.48) | POLBKMT2AAPLNRNPC1USP2 | |
| SCHEMBL13314027 | 0.78 | POLB (0.39) | POLBKMT2AAPLNRNPC1USP2 | |
| SCHEMBL2218343 | 0.74 | ALDH1A1 (0.40) | KMT2ANPC1USP2TP53PKM | |
| SCHEMBL29549138 | 0.72 | — | — | |
| SCHEMBL310954 | 0.72 | — | — | |
| SCHEMBL11631335 | 0.69 | NPC1 (0.72) | KMT2ANPC1USP2TP53PKM | |
| SCHEMBL16132008 | 0.67 | HRH3 (0.35) | POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20038399 | 0.67 | HCAR3 (0.42) | POLBKMT2AAPLNR | |
| SCHEMBL11636073 | 0.66 | RAB9A (0.49) | KMT2ANPC1USP2TP53PKM | |
| SCHEMBL22912926 | 0.66 | DRD2 (0.32) | NPC1USP2TP53PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114540846-B | Synthesis method of 1,2, 4-triazolo six-membered nitrogen heterocycle-3-amine | 五邑大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-114540846-A | Synthetic method of 1,2, 4-triazolo hexa-nitrogen heterocyclic-3-amine | 五邑大学 | 2022-05-27 | — | — | CN | disclosed |