Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 6/20 | 0.68 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.68 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.68 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3564730 | 0.88 | CHRNB4 (0.68) | CHRNB4CHRNA3CHRNB2CHRNA4KDM4E | |
| SCHEMBL27633054 | 0.85 | ACHE (0.52) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL19038337 | 0.85 | BCHE (0.72) | KDM4EBCHEMAOB | |
| SCHEMBL27752879 | 0.84 | CHRNB2 (0.61) | CHRNB4CHRNA3CHRNB2CHRNA4KDM4E | |
| Hydrochloric Acid SCHEMBL27454368 | 0.81 | CHRNB2 (0.57) | CHRNB4CHRNA3CHRNB2CHRNA4KDM4E | |
| SCHEMBL17440417 | 0.80 | CHRNB2 (0.58) | CHRNB4CHRNA3CHRNB2CHRNA4BCHE | |
| SCHEMBL17440420 | 0.80 | CHRNB2 (0.58) | CHRNB4CHRNA3CHRNB2CHRNA4BCHE | |
| SCHEMBL27703174 | 0.79 | CHRNB2 (0.54) | CHRNB4CHRNA3CHRNB2CHRNA4KDM4E | |
| SCHEMBL7005697 | 0.78 | KDM4E (0.75) | CHRNB4CHRNA3CHRNB2CHRNA4KDM4E | |
| SCHEMBL9685669 | 0.77 | BCHE (0.60) | BCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1374959-A | Piperidine quinolyl propyl derivatives, preparation method and compositions containing same | AVENTIS PHARMA SA (FR) | 2002-10-16 | — | — | CN | disclosed |