Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074374 | 0.80 | POLB (0.59) | GFERL3MBTL1USP2POLBMAPT | |
| SCHEMBL894337 | 0.77 | HPGD (0.56) | NR3C1MEN1KMT2ACA12CA1 | |
| SCHEMBL1664948 | 0.77 | KDM4E (0.61) | L3MBTL1KDM4EUSP2POLBMAPT | |
| SCHEMBL6074241 | 0.71 | CA1 (0.44) | GFERL3MBTL1KDM4EMAPTNPC1 | |
| SCHEMBL3555917 | 0.70 | HPGD (0.62) | L3MBTL1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL3558724 | 0.70 | LMNA (0.56) | KDM4EMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6982597 | 0.69 | ALDH1A1 (0.53) | GFERL3MBTL1USP2POLBMAPT | |
| SCHEMBL6074446 | 0.69 | LMNA (0.61) | USP2POLBMAPTALDH1A1DRD2 | |
| SCHEMBL7302963 | 0.69 | ALDH1A1 (0.47) | KDM4EUSP2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23355702 | 0.68 | L3MBTL3 (0.44) | GFERL3MBTL1ITGB3ITGA2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1455771-A | Cyclic amine phenyl Beta-3 adrenergic receptor agonists | WYETH LTD (US) | 2003-11-12 | — | — | CN | disclosed |