Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048873 | 0.87 | MLYCD (0.54) | L3MBTL1MLYCDHPGDCA2NAAA | |
| SCHEMBL27619609 | 0.85 | NAAA (0.50) | FOLH1L3MBTL1MLYCDCA2NAAA | |
| SCHEMBL27619621 | 0.85 | NAAA (0.48) | L3MBTL1HPGDCA2NAAAHDAC3 | |
| SCHEMBL5044219 | 0.84 | MLYCD (0.48) | L3MBTL1MLYCDHPGDHDAC3HDAC1 | |
| SCHEMBL5045568 | 0.83 | FOLH1 (0.46) | FOLH1L3MBTL1MLYCDHPGDCA2 | |
| SCHEMBL1856841 | 0.82 | FOLH1 (0.48) | FOLH1L3MBTL1MLYCDHPGDCA2 | |
| SCHEMBL5044055 | 0.80 | MLYCD (0.51) | MLYCDNAAAHDAC3HDAC1HDAC2 | |
| SCHEMBL5044232 | 0.78 | MAPK14 (0.49) | MLYCDHPGDHDAC3HDAC1SMN1; SMN2 | |
| SCHEMBL24153985 | 0.77 | L3MBTL1 (0.73) | FOLH1L3MBTL1MLYCDCA2NAAA | |
| SCHEMBL23627359 | 0.77 | L3MBTL1 (0.73) | FOLH1L3MBTL1MLYCDCA2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | disclosed |