Sugi Predict

Sugi Predict / Compounds / Butane

Butane

Butane

SCHEMBL2875433

CCCC.C[Si](C)(C)OC(=O)CCC(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FFAR3 O14843 1/20 0.44
▸ HDAC3 O15379 1/20 0.44
▸ HDAC1 Q13547 1/20 0.44
▸ HDAC2 Q92769 1/20 0.44
▸ HDAC8 Q9BY41 1/20 0.44
▸ EGLN1 Q9GZT9 2/20 0.43
▸ KDM6B O15054 1/20 0.43
▸ KDM5C P41229 1/20 0.43
▸ PHF8 Q9UPP1 1/20 0.43
▸ KDM2A Q9Y2K7 1/20 0.43
▸ AKR1B1 P15121 1/20 0.39
▸ LMNA P02545 2/20 0.39
▸ ALKBH5 Q6P6C2 1/20 0.39
▸ SUCNR1 Q9BXA5 1/20 0.39
▸ GPR84 Q9NQS5 7/20 0.38
▸ PPARG P37231 7/20 0.38
▸ PPARD Q03181 7/20 0.38
▸ PPARA Q07869 7/20 0.38
▸ HDAC11 Q96DB2 5/20 0.38
▸ TSHR P16473 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8136987 0.93 EGLN1 (0.48) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL4303758 0.83 TSHR (0.45) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL466165 0.81 ALDH1A1 (0.55) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL8467025 0.80 TSHR (0.52) AKR1B1LMNAGPR84PPARGPPARD
Butane SCHEMBL5906885 0.77 ALDH1A1 (0.62) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL6658596 0.76 AKR1B1 (0.43) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL19858487 0.76 DGKA (0.54) AKR1B1LMNAGPR84PPARGPPARD
SCHEMBL19858542 0.76 CYP1A2 (0.48) LMNATSHRALDH1A1ALOX15HSD17B10
Succinic Acid SCHEMBL2363993 0.75 FFAR3 (0.73) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL23295139 0.75 ALDH1A1 (0.50) LMNATSHRALDH1A1TDP1SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 — — EP claimed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 — — EP disclosed
CN-112204055-B Polypropylene composition and molded article 巴塞尔聚烯烃意大利有限公司 2022-01-18 — — CN disclosed
CN-112789296-A Polypropylene composition and molded article 巴塞尔聚烯烃意大利有限公司 2021-05-11 — — CN disclosed
US-8822366-B2 Solid titanium catalyst component, catalyst for olefin polymerization and process for polymerizing olefin MITSUI CHEMICALS, INC. (JP) 2014-09-02 — — US disclosed
EP-2697271-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-02-19 — — EP disclosed
EP-2206731-B1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD MITSUI CHEMICALS INC (JP) 2013-08-28 — — EP disclosed
WO-2012139897-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2012-10-18 — — WO disclosed
US-20100227991-A1 SOLID TITANIUM CATALYST COMPONENT, CATALIST FOR OLEFIN POLYMERIZATION AND PROCESS FOR POLYMERIZING OLEFIN MITSUI CHEMICALS, INC. (JP) 2010-09-09 — — US disclosed
EP-2206731-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD Mitsui Chemicals, Inc. (JP) 2010-07-14 — — EP disclosed