Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545806 | 0.92 | TSHR (0.39) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL6661355 | 0.91 | TSHR (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL14735468 | 0.86 | CES1 (0.41) | TSHRALDH1A1MAPTPAM | |
| SCHEMBL6546145 | 0.86 | TSHR (0.44) | TSHRALDH1A1TDP1MAPTPAM | |
| SCHEMBL2599070 | 0.86 | ALDH1A1 (0.44) | AKR1B1TSHRALDH1A1PAM | |
| SCHEMBL4643559 | 0.83 | NAAA (0.39) | TSHRALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4641456 | 0.81 | FAAH (0.37) | TSHRALDH1A1TDP1MAPTPAM | |
| SCHEMBL4644370 | 0.81 | DGKA (0.37) | TSHRALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4644437 | 0.81 | DGKA (0.33) | AKR1B1TSHRALDH1A1MAPTPAM | |
| SCHEMBL570531 | 0.80 | NAAA (0.42) | TSHRALDH1A1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005302-A1 | PROCESS FOR THE PREPARATION OF ACYLOXYSILANES | SIGMA COATINGS B.V. (NL) | 2004-01-15 | — | — | WO | disclosed |