Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 15/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 15/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16216397 | 0.81 | AAK1 (0.37) | PTGS1PTGS2MEN1KMT2ATSHR | |
| SCHEMBL16207402 | 0.81 | AAK1 (0.37) | PTGS1PTGS2MEN1KMT2ATSHR | |
| SCHEMBL28821875 | 0.79 | CES2 (0.35) | PTGS1PTGS2APPHPGD | |
| SCHEMBL1679175 | 0.76 | PTGS1 (0.51) | PTGS1PTGS2MEN1KMT2AFABP2 | |
| SCHEMBL23095908 | 0.76 | PDE2A (0.35) | ADRA2B | |
| SCHEMBL12413927 | 0.76 | GABRA1 (0.38) | — | |
| SCHEMBL19182931 | 0.76 | PTGS1 (0.54) | PTGS1PTGS2MEN1KMT2AFABP2 | |
| SCHEMBL31117279 | 0.76 | PTGS1 (0.54) | PTGS1PTGS2MEN1KMT2AFABP2 | |
| SCHEMBL19182930 | 0.76 | PTGS1 (0.54) | PTGS1PTGS2MEN1KMT2AFABP2 | |
| SCHEMBL16868771 | 0.74 | TRPV4 (0.42) | PTGS1PTGS2APPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114630823-A | GLP-1R modulating compounds | 吉利德科学公司 | 2022-06-14 | — | — | CN | disclosed |