Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 7/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.55 |
| ▸ | IDE | P14735 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1041663 | 0.81 | NCF1 (0.81) | NCF1ADRB2GAA | |
| SCHEMBL27635274 | 0.80 | HTR6 (0.50) | NCF1MEN1KMT2AHTR6HTR1A | |
| SCHEMBL27656331 | 0.77 | HTR5A (0.60) | NCF1HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL1043251 | 0.77 | NCF1 (0.70) | NCF1ADRB2MEN1KMT2ACLK1 | |
| SCHEMBL30058999 | 0.77 | NCF1 (0.70) | NCF1ADRB2MEN1KMT2ACLK1 | |
| SCHEMBL27605977 | 0.76 | HTR3E (0.44) | MEN1KMT2AHTR1AKDM4EMAPT | |
| SCHEMBL1042083 | 0.76 | NCF1 (0.68) | NCF1ADRB2MEN1KMT2ACLK1 | |
| SCHEMBL1042082 | 0.76 | NCF1 (0.68) | NCF1ADRB2MEN1KMT2ACLK1 | |
| SCHEMBL27674608 | 0.75 | HTR3E (0.43) | MEN1KMT2AHTR1AHTR1DHTR1B | |
| SCHEMBL27885936 | 0.75 | NCF1 (0.55) | NCF1ADRB2IDEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1694873-A | Vanilloid receptor ligands and their use in treatments | AMGEN INC (US) | 2005-11-09 | — | — | CN | disclosed |