Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | RBP4 | P02753 | 6/20 | 0.39 |
| ▸ | TTR | P02766 | 3/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599587 | 0.94 | POLB (0.44) | POLBHTR7RBP4TTRHTR1A | |
| SCHEMBL28754613 | 0.90 | RBP4 (0.42) | RBP4TTRCYP2D6FFAR4 | |
| SCHEMBL27618132 | 0.89 | POLB (0.48) | POLBRBP4TTRCHRNB4CHRNA3 | |
| SCHEMBL27599579 | 0.86 | POLB (0.40) | POLBKCNN4HTR7HTR2BHTR4 | |
| SCHEMBL27599339 | 0.85 | POLB (0.42) | POLBKCNN4HTR7HTR2BHTR4 | |
| SCHEMBL1475707 | 0.84 | DCPS (0.46) | POLBHTR7HTR2BHTR4HTR2C | |
| SCHEMBL27618123 | 0.80 | HTR2C (0.37) | POLBHTR2CCYP2D6FFAR4 | |
| SCHEMBL27599441 | 0.80 | DRD2 (0.45) | HTR7RBP4CHRNB4CHRNA3HTR1A | |
| SCHEMBL5213268 | 0.79 | MAOA (0.42) | RBP4TTRHTR2A | |
| SCHEMBL27617858 | 0.79 | HTR4 (0.38) | POLBKCNN4HTR7HTR2BHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100389113-C | Nitrogen-containing heterocyclic compound and drug containing same | EISAI CO LTD (JP) | 2008-05-21 | — | — | CN | disclosed |
| CN-1630650-A | Nitrogen-containing heterocyclic compound and drug containing same | EISAI CO LTD (JP) | 2005-06-22 | — | — | CN | disclosed |