Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214618 | 0.85 | ACHE (0.43) | ACHEALDH1A1KDM4EHPGDKCNH2 | |
| SCHEMBL29099801 | 0.83 | KMT2A (0.51) | APPALDH1A1KDM4ESMN1; SMN2TDP1 | |
| Aminacrine SCHEMBL8711062 | 0.80 | ACHE (0.60) | APPACHEALDH1A1KDM4EHPGD | |
| SCHEMBL787604 | 0.72 | KDM4E (0.57) | APPACHEALDH1A1KDM4EHPGD | |
| SCHEMBL20475930 | 0.72 | ALDH1A1 (0.57) | APPACHEALDH1A1KDM4EHPGD | |
| SCHEMBL16836308 | 0.72 | TLR8 (0.57) | APPACHEALDH1A1KDM4EHPGD | |
| SCHEMBL16836489 | 0.70 | TLR8 (0.58) | APPACHEALDH1A1KDM4EHPGD | |
| Aminacrine SCHEMBL8713522 | 0.69 | ACHE (0.58) | APPACHEALDH1A1KDM4EHPGD | |
| SCHEMBL10589352 | 0.68 | MEN1 (0.45) | APPALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL19916032 | 0.68 | LOXL2 (0.53) | APPALDH1A1KDM4ESMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1747953-A | Aryl / hetaryl substituted imidazoquinolines. | 3M INNOVATIVE PROPERTIES CO (US) | 2006-03-15 | — | — | CN | disclosed |