Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 12/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12563482 | 0.79 | PDE2A (0.44) | CTSANPSR1HSD17B10MAPT | |
| SCHEMBL27816822 | 0.79 | IKBKB (0.49) | KDM4EL3MBTL1HSD17B10ALOX15MEN1 | |
| SCHEMBL31604695 | 0.76 | PTPN1 (0.53) | — | |
| SCHEMBL28788541 | 0.75 | HDAC1 (0.46) | KDM4EHSD17B10MAPT | |
| SCHEMBL1988924 | 0.75 | PDE2A (0.39) | CTSANPSR1HSD17B10MAPT | |
| SCHEMBL12697463 | 0.75 | PDE2A (0.39) | CTSANPSR1HSD17B10MAPT | |
| SCHEMBL2638386 | 0.74 | ADRB2 (0.53) | — | |
| SCHEMBL1660892 | 0.72 | BCHE (0.42) | — | |
| SCHEMBL487560 | 0.72 | ALDH1A1 (0.50) | KDM4EFYNNPSR1HSD17B10MAPT | |
| SCHEMBL8940819 | 0.71 | HDAC4 (0.50) | FYNMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307394-B1 | SULPHONAMIDES AS VANILLOID RECEPTOR ANTAGONIST | AMOREPACIFIC CORP (KR) | 2012-09-26 | — | — | EP | disclosed |
| WO-2010002209-A2 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2010-01-07 | — | — | WO | disclosed |