Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 13/20 | 0.39 |
| ▸ | DRD4 | P21917 | 12/20 | 0.39 |
| ▸ | DRD3 | P35462 | 12/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812202 | 0.93 | HSD11B1 (0.43) | HDAC4HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL7490230 | 0.83 | HDAC4 (0.42) | HDAC4HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL28658382 | 0.81 | TPMT (0.33) | — | |
| SCHEMBL2720401 | 0.81 | CA1 (0.37) | — | |
| SCHEMBL28108261 | 0.81 | CA1 (0.36) | — | |
| SCHEMBL7176061 | 0.81 | DRD2 (0.52) | HDAC4HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL2572169 | 0.81 | AKR1C1 (0.42) | HDAC4HSD11B1DRD3 | |
| SCHEMBL28649793 | 0.80 | PARP1 (0.43) | HSD11B1 | |
| SCHEMBL6036780 | 0.76 | HDAC4 (0.47) | HDAC4HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL17698403 | 0.76 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585603-A | Prostaglandin EP4Receptor antagonist compounds | 赫普泰雅治疗有限公司 | 2022-06-03 | — | — | CN | disclosed |