Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 3/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28755810 | 0.81 | HDAC4 (0.41) | — | |
| SCHEMBL2720401 | 0.81 | CA1 (0.37) | CA1CA2FPR2 | |
| SCHEMBL5644519 | 0.81 | OPRM1 (0.39) | CA1CA2OPRM1TPMTPTPN2 | |
| SCHEMBL2572169 | 0.81 | AKR1C1 (0.42) | OPRM1 | |
| SCHEMBL17698403 | 0.76 | ALDH1A1 (0.41) | AVPR2AVPR1ALMNA | |
| SCHEMBL15258670 | 0.76 | MAPT (0.46) | CA1CA2LMNA | |
| SCHEMBL3813595 | 0.75 | ALDH1A1 (0.36) | CA1CA2FPR2LMNA | |
| SCHEMBL3812202 | 0.75 | HSD11B1 (0.43) | — | |
| SCHEMBL3816037 | 0.75 | FFAR1 (0.41) | CA1CA2LMNA | |
| SCHEMBL28046111 | 0.75 | OPRM1 (0.35) | CA1CA2OPRM1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061977-B | 1, 2-dihydro-3H-pyrrolo [1,2-C ] imidazol-3-one derivatives and their use as antibacterial agents | 爱杜西亚药品有限公司 | 2018-10-26 | — | — | CN | disclosed |
| CN-106061977-A | 1, 2-dihydro-3H-pyrrolo [1,2-C ] imidazol-3-one derivatives and their use as antibacterial agents | 埃科特莱茵药品有限公司 | 2016-10-26 | — | — | CN | disclosed |