Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.41 |
| ▸ | DRD2 | P14416 | 11/20 | 0.41 |
| ▸ | DRD4 | P21917 | 11/20 | 0.41 |
| ▸ | DRD3 | P35462 | 11/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036780 | 0.93 | HDAC4 (0.47) | HDAC4HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL10604944 | 0.84 | WDR91 (0.41) | HDAC4HSD11B1CCR2 | |
| SCHEMBL7176061 | 0.83 | DRD2 (0.52) | HDAC4HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL28755810 | 0.83 | HDAC4 (0.41) | HDAC4HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL4699835 | 0.82 | AKR1C1 (0.45) | HDAC4HSD11B1DRD3 | |
| SCHEMBL4697560 | 0.81 | CA1 (0.38) | — | |
| SCHEMBL6206134 | 0.78 | OPRM1 (0.49) | HSD11B1 | |
| SCHEMBL3812202 | 0.77 | HSD11B1 (0.43) | HDAC4HSD11B1DRD2DRD4DRD3 | |
| SCHEMBL6036843 | 0.74 | AKR1C1 (0.52) | HDAC4HSD11B1 | |
| SCHEMBL6202645 | 0.74 | OPRM1 (0.38) | HSD11B1DRD2DRD4DRD3CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| EP-0414059-B1 | Dihalogenovinylbenzylesters, process and starting material for their preparation and their utilization for the control of parasites | BASF AG (DE) | 1993-10-27 | — | — | EP | disclosed |
| EP-0347693-B1 | BENZONITRILES, BENZALDEHYDES AND BENZYL ALCOHOLS, AND PROCESSES FOR THEIR PRODUCTION | BASF Aktiengesellschaft (DE) | 1992-09-09 | — | — | EP | disclosed |
| EP-0347694-B1 | PYRETHROIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATING PESTS | BASF Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | disclosed |
| EP-0414059-A1 | Dihalogenovinylbenzylesters, process and starting material for their preparation and their utilization for the control of parasites | BASF Aktiengesellschaft (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0347693-A1 | Benzonitriles, benzaldehydes and benzyl alcohols, and processes for their production | BASF Aktiengesellschaft (DE) | 1989-12-27 | — | — | EP | disclosed |
| EP-0347694-A1 | Pyrethroids, process for their preparation and their use in combating pests | BASF Aktiengesellschaft (DE) | 1989-12-27 | — | — | EP | disclosed |