Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124956 | 0.85 | HRH3 (0.56) | NOTUMHRH3HTTDRD2DRD4 | |
| SCHEMBL3427936 | 0.83 | HTR1A (0.53) | NOTUMHRH3HTR1ADRD2DRD4 | |
| SCHEMBL16685154 | 0.83 | NOTUM (0.51) | NOTUMHDAC1HDAC6HTR1AHTR2C | |
| SCHEMBL11304976 | 0.81 | HTR6 (0.62) | NOTUMHDAC1HDAC6HTR1ADRD2 | |
| SCHEMBL2625801 | 0.77 | NOTUM (0.59) | NOTUMHTR2CHTR2BDRD2DRD4 | |
| SCHEMBL12656140 | 0.77 | NOTUM (0.51) | NOTUMHRH3HTTHTR2CHTR2B | |
| SCHEMBL2271564 | 0.76 | HRH3 (0.41) | HRH3HTR1ADRD2 | |
| SCHEMBL13228227 | 0.76 | NOTUM (0.53) | NOTUMHRH3HTR2CDRD2DRD4 | |
| SCHEMBL26890101 | 0.76 | DRD2 (0.41) | HRH3HTR1AHTTHTR2CDRD2 | |
| SCHEMBL8209031 | 0.75 | TAAR1 (0.61) | NOTUMHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634443-A | Aromatic dihydropyrrole [2,3] cyclobutane compound and synthesis method thereof | 湖南科技学院 | 2022-06-17 | — | — | CN | disclosed |