Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213010 | 0.81 | SLC22A6 (0.32) | — | |
| SCHEMBL28979478 | 0.70 | ALDH1A1 (0.38) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| SCHEMBL28549412 | 0.70 | TSHR (0.38) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| SCHEMBL9809435 | 0.68 | — | — | |
| SCHEMBL28724770 | 0.68 | MEN1 (0.36) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| SCHEMBL28263308 | 0.65 | MEN1 (0.33) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL1355604 | 0.65 | — | — | |
| SCHEMBL6632566 | 0.62 | — | — | |
| SCHEMBL1030923 | 0.61 | TP53 (0.50) | MEN1ALDH1A1TSHRKMT2ATP53 | |
| Potassium Ion SCHEMBL29170915 | 0.61 | TP53 (0.30) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114470343-A | Lubricating coating and preparation method and application thereof | 珠海金导医疗科技有限公司 | 2022-05-13 | — | — | CN | disclosed |