Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 4/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 5/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656893 | 0.84 | TRPV3 (0.35) | ALKPTPN11KMOTRPV3 | |
| SCHEMBL27635865 | 0.80 | TRPV1 (0.35) | HRH4PTPN11KMOTRPV3 | |
| SCHEMBL907895 | 0.73 | CETP (0.42) | SOS1HRH4HRH3PTPN11 | |
| SCHEMBL908061 | 0.70 | CASP1 (0.39) | SOS1PRKD1PRKD2HRH4HRH3 | |
| SCHEMBL27635880 | 0.69 | KIT (0.34) | — | |
| SCHEMBL27635905 | 0.68 | ADORA3 (0.36) | TRPV3 | |
| SCHEMBL3881055 | 0.64 | EPHX2 (0.54) | — | |
| SCHEMBL27635986 | 0.62 | HSD11B1 (0.44) | — | |
| SCHEMBL3876842 | 0.61 | HSD11B1 (0.49) | — | |
| SCHEMBL25409176 | 0.61 | SOS1 (0.39) | SOS1PTPN11HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1823057-A | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORP (US) | 2006-08-23 | — | — | CN | disclosed |