Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4479470 | 0.80 | PTPN1 (0.48) | PTPN1GAAMGAMSIMGAM2 | |
| SCHEMBL4479473 | 0.80 | PTPN1 (0.48) | PTPN1GAAMGAMSIMGAM2 | |
| SCHEMBL29435848 | 0.64 | BACE1 (0.47) | PTPN1GAACYP19A1MAPK1KMT2A | |
| SCHEMBL30457085 | 0.63 | CTSK (0.49) | PTPN1GAAMGAMSIMGAM2 | |
| SCHEMBL14533455 | 0.60 | PTPN1 (0.48) | PTPN1GAAMGAMCYP19A1MAPK1 | |
| SCHEMBL27925921 | 0.60 | ESR1 (0.50) | GAACYP19A1MAPK1KMT2AMEN1 | |
| SCHEMBL1153975 | 0.58 | MAOA (0.50) | PTPN1CYP19A1MAPTPTGS2ESR1 | |
| SCHEMBL27662689 | 0.58 | PTPN1 (0.37) | PTPN1GAACYP19A1MAPK1KMT2A | |
| SCHEMBL30419021 | 0.58 | ALOX15 (0.46) | PTPN1GAAMGAMSIMGAM2 | |
| SCHEMBL6784264 | 0.58 | NQO2 (0.49) | PTPN1KMT2AMEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1816328-A | Therapeutic agent | TAKARA BIO INC (JP) | 2006-08-09 | — | — | CN | claimed |
| CN-1816328-A | Therapeutic agent | TAKARA BIO INC (JP) | 2006-08-09 | — | — | CN | disclosed |