Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PMM2 | O15305 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28766401 | 0.89 | ALDH1A1 (0.36) | KDM4ERECQLMAPTMEN1KMT2A | |
| SCHEMBL29089072 | 0.88 | KDM4E (0.33) | KDM4ERECQLALDH1A1 | |
| SCHEMBL29089042 | 0.87 | KDM4E (0.32) | KDM4ERECQLGAAALDH1A1EGFR | |
| SCHEMBL28766421 | 0.87 | ALDH1A1 (0.33) | KDM4ERECQLMAPTRAB9AMEN1 | |
| SCHEMBL28182028 | 0.76 | MAPT (0.33) | KDM4ERECQLMAPTMEN1KMT2A | |
| SCHEMBL28766416 | 0.75 | PRKCZ (0.34) | KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL29089070 | 0.73 | PSEN1 (0.32) | KDM4ERECQLMAPTMEN1KMT2A | |
| SCHEMBL27991414 | 0.72 | ALDH1A1 (0.39) | KDM4ERECQLMAPTRAB9AMEN1 | |
| SCHEMBL28043608 | 0.67 | OPRM1 (0.43) | KDM4ERECQLMAPTRAB9AKMT2A | |
| SCHEMBL28147769 | 0.64 | BRD4 (0.37) | KDM4EMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114560814-A | Synthesis method of substituted 2, 3-phthalazinone compound | 天津理工大学 | 2022-05-31 | — | — | CN | disclosed |