Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28766401 | 0.88 | ALDH1A1 (0.36) | KDM4ERECQLALDH1A1 | |
| SCHEMBL28766378 | 0.87 | KDM4E (0.35) | KDM4ERECQLALDH1A1EGFRERBB2 | |
| SCHEMBL29089072 | 0.87 | KDM4E (0.33) | KDM4ERECQLALDH1A1 | |
| SCHEMBL28766421 | 0.86 | ALDH1A1 (0.33) | KDM4ERECQLALDH1A1EGFRERBB2 | |
| SCHEMBL28766416 | 0.74 | PRKCZ (0.34) | KDM4EALDH1A1GAA | |
| SCHEMBL28182028 | 0.72 | MAPT (0.33) | KDM4ERECQLALDH1A1 | |
| SCHEMBL29089070 | 0.69 | PSEN1 (0.32) | KDM4ERECQL | |
| SCHEMBL27696136 | 0.68 | EGFR (0.35) | KDM4EALDH1A1EGFRERBB2GAA | |
| SCHEMBL27696148 | 0.67 | PTGS2 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL27696135 | 0.65 | LMNA (0.36) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114560814-B | Synthesis method of substituted 2, 3-naphthyridine ketone compound | 天津理工大学 | 2023-10-20 | — | — | CN | disclosed |