Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 13/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 13/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 13/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 13/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 13/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 13/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28182028 | 0.79 | MAPT (0.33) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28766401 | 0.73 | ALDH1A1 (0.36) | MAPTKDM4ERECQLMEN1KMT2A | |
| SCHEMBL28766378 | 0.73 | KDM4E (0.35) | MAPTKDM4ERECQLMEN1KMT2A | |
| SCHEMBL29089072 | 0.70 | KDM4E (0.33) | KDM4ERECQL | |
| SCHEMBL28766416 | 0.69 | PRKCZ (0.34) | MAPTKDM4E | |
| SCHEMBL28766421 | 0.69 | ALDH1A1 (0.33) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29089042 | 0.69 | KDM4E (0.32) | KDM4ERECQL | |
| SCHEMBL28089129 | 0.68 | BRD4 (0.49) | MAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27913881 | 0.67 | BRD4 (0.47) | MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7141507 | 0.65 | PSEN1 (0.30) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114560814-B | Synthesis method of substituted 2, 3-naphthyridine ketone compound | 天津理工大学 | 2023-10-20 | — | — | CN | disclosed |