Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404304 | 0.84 | ALDH1A1 (0.52) | MEP1BALDH1A1LMNAMAPK1HTT | |
| SCHEMBL12064314 | 0.84 | ALDH1A1 (0.52) | MEP1BALDH1A1LMNAMAPK1HTT | |
| SCHEMBL399676 | 0.84 | ALDH1A1 (0.52) | MEP1BALDH1A1LMNAMAPK1HTT | |
| SCHEMBL399832 | 0.84 | ALDH1A1 (0.52) | MEP1BALDH1A1LMNAMAPK1HTT | |
| SCHEMBL2876648 | 0.82 | MEP1B (0.48) | MEP1BALDH1A1LMNAMAPK1HTT | |
| SCHEMBL2258599 | 0.82 | MEP1B (0.54) | MEP1B | |
| SCHEMBL402286 | 0.81 | MEP1B (0.43) | MEP1BALDH1A1LMNAMAPK1HTT | |
| SCHEMBL402593 | 0.81 | BACE1 (0.47) | MEP1BALDH1A1LMNAMAPK1HTT | |
| SCHEMBL2256425 | 0.78 | ADAM17 (0.39) | MEP1BALDH1A1LMNAMAPK1HTT | |
| SCHEMBL5130164 | 0.78 | MEP1B (0.58) | MEP1BALDH1A1ADAM17ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084615-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100324025-A1 | Antibacterial Agents | UNIVERSITY OF WASHINGTON (US) | 2010-12-23 | — | — | US | disclosed |
| US-20090247506-A1 | Antibacterial agents | CHIRON CORPORATION | 2009-10-01 | — | — | US | disclosed |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | UNIVERSITY OF WASHINGTON (US) | 2009-06-25 | — | — | US | disclosed |
| US-20080269221-A1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2008-10-30 | — | — | US | disclosed |
| US-20070244197-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244197-A1 | Antibacterial agents | MRPL21, SI, PGLS | MEP1B 1047/4885ALDH1A1 782/4885LMNA 3397/4885 |
| US-20090247506-A1 | Antibacterial agents | MRPL21, SI, PGLS | MEP1B 1047/4885ALDH1A1 782/4885LMNA 3397/4885 |
| US-20080269221-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | MEP1B 1047/4885ALDH1A1 782/4885LMNA 3397/4885 |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | MEP1B 1047/4885ALDH1A1 782/4885LMNA 3397/4885 |
| US-20100324025-A1 | Antibacterial Agents | MRPL21, SI, PGLS | MEP1B 1047/4885ALDH1A1 782/4885LMNA 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.