Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5438533 | 0.77 | ALDH1A1 (0.58) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL26248824 | 0.74 | ALDH1A1 (0.58) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL8883524 | 0.72 | AHCY (0.60) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL9310418 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL29885678 | 0.71 | AHCY (0.63) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL9309087 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL28432979 | 0.70 | ADORA3 (0.51) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL8338176 | 0.69 | ALDH1A1 (0.56) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL8537379 | 0.69 | ALDH1A1 (0.56) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL2294538 | 0.68 | ALDH1A1 (0.68) | ALDH1A1LMNAALBMAPK1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146539-A | Use of pde7 inhibitors for the treatment of neuropathic pain | PFIZER LTD (GB) | 2008-03-19 | — | — | CN | disclosed |