Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 8/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29885678 | 0.88 | AHCY (0.63) | AHCYADORA3ALDH1A1LMNAALB | |
| SCHEMBL28432979 | 0.87 | ADORA3 (0.51) | AHCYADORA3ALDH1A1LMNAALB | |
| SCHEMBL28130881 | 0.85 | AHCY (0.63) | AHCYADORA3ALDH1A1LMNAALB | |
| SCHEMBL11161954 | 0.85 | AHCY (0.63) | AHCYADORA3ALDH1A1LMNAALB | |
| SCHEMBL9310418 | 0.83 | ALDH1A1 (0.58) | AHCYADORA3ALDH1A1LMNAALB | |
| SCHEMBL8885578 | 0.81 | ADORA3 (0.48) | AHCYADORA3ALDH1A1LMNAALB | |
| SCHEMBL8885117 | 0.81 | PNP (0.60) | AHCYADORA3STING1 | |
| SCHEMBL23600855 | 0.79 | STING1 (0.56) | ADORA3ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL28772469 | 0.79 | STING1 (0.56) | ADORA3ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL9445335 | 0.79 | ALDH1A1 (0.54) | ADORA3ALDH1A1LMNAALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631259-A | PURINE BASE DERIVATIVES FOR NUCLEOSIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| EP-0521463-A2 | Substituted cyclic cycloalkyltriols, process, intermediates for their preparation and their use as antiviral and antiparasitic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-07 | — | — | EP | disclosed |