SCHEMBL28772201

SCHEMBL28772201

C#Cc1ccccc1NS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.64
ALDH1A1 P00352 4/20 0.64
CYP2C9 P11712 2/20 0.64
CYP2C19 P33261 2/20 0.64
MAPT P10636 2/20 0.64
USP2 O75604 1/20 0.64
POLB P06746 1/20 0.64
NOD2 Q9HC29 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
CA2 P00918 4/20 0.63
CA9 Q16790 4/20 0.63
CA1 P00915 3/20 0.63
CA4 P22748 2/20 0.63
CA7 P43166 2/20 0.63
KEAP1 Q14145 1/20 0.59
NFE2L2 Q16236 1/20 0.59
CA12 O43570 2/20 0.57
MCOLN3 Q8TDD5 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.56
TSHR P16473 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6553546 0.84 LMNA (0.64) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL29083812 0.84 CA2 (0.63) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL29083802 0.84 CA1 (0.59) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL23380497 0.84 ALDH1A1 (0.60) LMNAALDH1A1TSHRKMT2AHTT
SCHEMBL28826012 0.84 KEAP1 (0.65) LMNAALDH1A1MAPTPOLBL3MBTL1
SCHEMBL2068526 0.83 LMNA (0.82) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL29083793 0.82 CA2 (0.56) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL30100593 0.82 SLC16A3 (0.65) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL28929932 0.82 SLC16A3 (0.65) LMNAALDH1A1CYP2C9CYP2C19MAPT
SCHEMBL28553190 0.81 LMNA (0.56) LMNAALDH1A1CYP2C9CYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114807985-B Preparation method of 2, 3-indolyl imine compound 南京林业大学 2025-04-22 CN claimed
CN-114807985-B Preparation method of 2, 3-indolyl imine compound 南京林业大学 2025-04-22 CN disclosed
CN-114656395-B Synthesis method of 2, 3-diamine indole compound 南京林业大学 2025-04-11 CN disclosed
CN-114807985-A Preparation method of 2, 3-indoleimine compound 南京林业大学 2022-07-29 CN disclosed
CN-114656395-A Synthetic method of 2, 3-diaminoindole compound 南京林业大学 2022-06-24 CN disclosed