Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23200280 | 0.85 | KCNA5 (0.57) | LMNAALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL28772201 | 0.84 | LMNA (0.64) | LMNAALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL22654320 | 0.84 | ALDH1A1 (0.54) | LMNAALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL30949870 | 0.84 | ALDH1A1 (0.54) | LMNAALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL4649581 | 0.84 | HSD17B2 (0.63) | ALDH1A1CA2CA1SLC22A12RXFP1 | |
| SCHEMBL8711719 | 0.84 | STAT3 (0.65) | LMNAALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL2068526 | 0.83 | LMNA (0.82) | LMNAALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL30100593 | 0.82 | SLC16A3 (0.65) | LMNAALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL28929932 | 0.82 | SLC16A3 (0.65) | LMNAALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL28375872 | 0.81 | SLC16A3 (0.64) | LMNAALDH1A1MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935234-A1 | ENZYME INHIBITORS | University of Sunderland (GB) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014096864-A9 | ENZYME INHIBITORS | UNIVERSITY OF SUNDERLAND (GB) | 2015-03-05 | — | — | WO | disclosed |
| WO-2014096864-A1 | ENZYME INHIBITORS | UNIVERSITY OF SUNDERLAND (GB) | 2014-06-26 | — | — | WO | disclosed |
| EP-1174028-B1 | SULFONAMIDE DERIVATIVES | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-20040023938-A1 | Sulfonamide derivatives | TABUCHI TAKANORI (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6586617-B1 | Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023938-A1 | Sulfonamide derivatives | FPR1, MRM1, SULT1E1 | LMNA 3028/4885ALDH1A1 453/4885MAPT 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.