Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169434 | 0.84 | MTNR1A (0.55) | CYP1A2CYP2A6MTNR1AHTR2AMTNR1B | |
| SCHEMBL8125066 | 0.84 | HDAC8 (0.54) | CYP1A2CYP2A6HDAC8KMT2AMEN1 | |
| SCHEMBL31612942 | 0.81 | LMNA (0.56) | CYP1A2CYP2A6KMT2AMEN1NPC1 | |
| SCHEMBL9068308 | 0.79 | NPC1 (0.53) | CYP1A2CYP2A6HDAC8KMT2AMEN1 | |
| 1-Naphthol SCHEMBL2016852 | 0.79 | CYP1A2 (0.63) | CYP1A2CYP2A6MTNR1AKMT2AMEN1 | |
| SCHEMBL3248269 | 0.78 | HTR2A (0.54) | MTNR1AHTR2AMTNR1B | |
| SCHEMBL29038965 | 0.77 | CYP1A2 (0.47) | CYP1A2CYP2A6MTNR1AHTR2AHDAC8 | |
| SCHEMBL7176235 | 0.77 | CYP1A2 (0.46) | CYP1A2KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL31411902 | 0.77 | ESR2 (0.64) | CYP1A2CYP2A6KMT2AMEN1NPC1 | |
| 1-Naphthol SCHEMBL7584597 | 0.76 | CYP1A2 (0.55) | CYP1A2CYP2A6KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101291931-A | 9-azabicyclo [3.3.1]nonane derivatives as monoamine reuptake inhibitors | ORGANON NV (NL) | 2008-10-22 | — | — | CN | disclosed |