Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27728779 | 0.99 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3POLBL3MBTL1 | |
| SCHEMBL28780742 | 0.85 | PIM1 (0.43) | SLC6A4SLC6A2SLC6A3ADRB1KCNH2 | |
| SCHEMBL3017728 | 0.82 | ADRB1 (0.56) | POLBALDH1A1HTR3EHTR3BADRB1 | |
| Hydrochloric Acid SCHEMBL2524208 | 0.81 | ADRB1 (0.54) | POLBALDH1A1HTR3EHTR3BADRB1 | |
| SCHEMBL27728780 | 0.77 | ALDH1A1 (0.50) | SLC6A4SLC6A2SLC6A3ALDH1A1TSHR | |
| SCHEMBL7647236 | 0.77 | ADRB1 (0.52) | POLBALDH1A1ADRB1HTR2AHTR2C | |
| SCHEMBL27744781 | 0.77 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3LIPEALDH1A1 | |
| SCHEMBL19003593 | 0.76 | MGLL (0.39) | POLBL3MBTL1ALDH1A1ADRB1KCNH2 | |
| SCHEMBL7943366 | 0.75 | MAPT (0.38) | POLBL3MBTL1ALDH1A1HTR3EHTR3B | |
| SCHEMBL4487460 | 0.75 | ADRB1 (0.50) | SLC6A4SLC6A2SLC6A3HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421258-B | Sulfonyl-substituted bicyclic compounds as PPAR modulators | KALYPSYS INC | 2013-08-21 | — | — | CN | disclosed |
| CN-101421258-A | Sulfonyl-substituted bicyclic compounds as PPAR modulators | KALYSPSYS INC (US) | 2009-04-29 | — | — | CN | disclosed |
| CN-101374813-A | Arylsulfonamide and sulfonyl compounds as PPAR modulators and methods of treating metabolic disorders | KALYPSYS INC (US) | 2009-02-25 | — | — | CN | disclosed |