Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201711 | 0.93 | HTT (0.39) | HSD11B1MGLLHDAC3HDAC4HDAC1 | |
| SCHEMBL27152786 | 0.92 | HTT (0.39) | HSD11B1MGLLHDAC3HDAC4HDAC1 | |
| SCHEMBL27125679 | 0.91 | ITGB3 (0.38) | HSD11B1MGLLCCR3TSHRNPSR1 | |
| SCHEMBL30014221 | 0.91 | ITGB3 (0.38) | HSD11B1MGLLCCR3TSHRNPSR1 | |
| SCHEMBL27147744 | 0.91 | NAMPT (0.36) | HSD11B1MGLLHDAC3HDAC4HDAC1 | |
| SCHEMBL29201758 | 0.91 | HTT (0.40) | HSD11B1MGLL | |
| SCHEMBL27139369 | 0.91 | FFAR4 (0.40) | HSD11B1MGLLHDAC3HDAC4HDAC1 | |
| SCHEMBL27143092 | 0.90 | MGLL (0.42) | HSD11B1MGLLCCR3TSHRNPSR1 | |
| SCHEMBL29201746 | 0.89 | MGLL (0.39) | HSD11B1MGLLCCR3TSHRNPSR1 | |
| SCHEMBL28868792 | 0.89 | HSD11B1 (0.40) | HSD11B1MGLLCCR3TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232114-B | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| WO-2022223034-A1 | SOS1 DEGRADATION AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海领泰生物医药科技有限公司 | 2022-10-27 | — | — | WO | disclosed |
| CN-115232114-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |