Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201711 | 0.95 | HTT (0.39) | HTTDRD2DRD3LIPGADRB2 | |
| SCHEMBL27152786 | 0.94 | HTT (0.39) | HTTDRD2DRD3LIPGADRB2 | |
| SCHEMBL28783591 | 0.91 | CCR3 (0.38) | HTTADRB2HSD11B1MGLL | |
| SCHEMBL29277059 | 0.91 | HSD11B1 (0.39) | HSD11B1MGLL | |
| SCHEMBL31677216 | 0.90 | HTT (0.39) | HTTSPIN1SMYD3HSD11B1MGLL | |
| SCHEMBL27146833 | 0.89 | MGLL (0.38) | HTTDRD2DRD3LIPGADRB2 | |
| SCHEMBL28978059 | 0.87 | HPGD (0.44) | HSD11B1MGLL | |
| SCHEMBL27143092 | 0.86 | MGLL (0.42) | LIPGHSD11B1MGLL | |
| SCHEMBL29201746 | 0.86 | MGLL (0.39) | HSD11B1MGLL | |
| SCHEMBL28868792 | 0.86 | HSD11B1 (0.40) | LIPGHSD11B1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |