Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815909 | 0.79 | MAPT (0.50) | LMNAESRRGALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2099233 | 0.75 | LMNA (0.53) | LMNATHRBPOLBRECQLTDP1 | |
| SCHEMBL6068233 | 0.75 | CES2 (0.55) | LMNARAB9ASMN1; SMN2L3MBTL1BRD4 | |
| SCHEMBL661247 | 0.74 | CYP1A2 (0.56) | LMNAESRRGALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3621390 | 0.73 | P2RX7 (0.56) | LMNAESRRGALDH1A1THRBPOLB | |
| SCHEMBL12121033 | 0.73 | LOXL2 (0.49) | LMNAESRRGRAB9ASMN1; SMN2BRD4 | |
| SCHEMBL2987879 | 0.73 | KMT2A (0.63) | ESRRGALDH1A1THRBPOLBRECQL | |
| SCHEMBL28460519 | 0.73 | POLB (0.72) | LMNAALDH1A1THRBPOLBRECQL | |
| SCHEMBL3346723 | 0.72 | DGAT1 (0.54) | LMNAALDH1A1RAB9ASMN1; SMN2POLB | |
| SCHEMBL3117436 | 0.72 | CRBN (0.45) | LMNAESRRGHTR2AMCHR1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553461-A | 4-substituted phenoxyphenylacetic acid derivatives | ARRAY BIOPHARMA INC (US) | 2009-10-07 | — | — | CN | disclosed |