SCHEMBL28787264

SCHEMBL28787264

CC(CCN(C)[SH](=O)=O)C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33
GABRR1 P24046 2/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7508980 0.80 CHRNB2 (0.36) CHRNB2CHRNB4CHRNA3CHRNA4GABRR1
Hydrochloric Acid SCHEMBL21197508 0.78 CHRNB2 (0.35) CHRNB2CHRNB4CHRNA3CHRNA4GABRR1
SCHEMBL27847066 0.74 MEN1 (0.37) CHRNB2CHRNB4CHRNA3CHRNA4GABRR1
SCHEMBL6668916 0.72 NPSR1 (0.35) GABRR1
SCHEMBL7159682 0.72 NOS2 (0.38) CHRNB2CHRNB4CHRNA3CHRNA4NOS3
Hydrochloric Acid SCHEMBL21197485 0.71 ALDH1A1 (0.37) CHRNB2CHRNB4CHRNA3CHRNA4NOS3
SCHEMBL28693236 0.71 ALDH1A1 (0.40) NOS3NOS1NOS2
SCHEMBL15340966 0.69 BLM (0.44) CHRNB2CHRNB4CHRNA3CHRNA4GABRR1
SCHEMBL22044214 0.67
SCHEMBL1515383 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114727959-A Modification of plant messenger packages with charged lipids 旗舰创业创新六公司 2022-07-08 CN disclosed