Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286625 | 0.82 | — | — | |
| SCHEMBL27817206 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| Water SCHEMBL28320107 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL28056814 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| Styrene SCHEMBL523206 | 0.77 | ALDH1A1 (0.64) | ALDH1A1TSHRHTTKCNN4TP53 | |
| Diethylamine SCHEMBL27864499 | 0.72 | TP53 (0.36) | HTTKCNN4TP53ADRB2KDM1A | |
| Diethylamine SCHEMBL27874184 | 0.69 | TP53 (0.42) | HTTKCNN4TP53ADRB2KDM1A | |
| SCHEMBL2274476 | 0.68 | KCNN4 (0.35) | HTTKCNN4TP53ADRB2GAA | |
| Biphenyl SCHEMBL12984366 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HTTKCNN4TP53ADRB2 | |
| (Z)-1,2-Diphenylethene SCHEMBL9179151 | 0.67 | RELA (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471581-A | Curable composition for semiconductor encapsulation | ADEKA CORP | 2012-05-23 | — | — | CN | disclosed |