SCHEMBL28798018

SCHEMBL28798018

O=C(O)CCN1CCC[C@H]2CNC[C@H]21

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 5/20 0.37
LTA4H P09960 2/20 0.36
ITGB3 P05106 5/20 0.33
ITGA2B P08514 5/20 0.33
OPRD1 P41143 2/20 0.33
NR1H4 Q96RI1 1/20 0.32
OPRM1 P35372 1/20 0.32
OPRK1 P41145 1/20 0.32
OPRL1 P41146 1/20 0.32
OGFRL1 Q5TC84 1/20 0.32
F2R P25116 4/20 0.32
CHRM1 P11229 2/20 0.32
CYP1A2 P05177 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DRD2 P14416 1/20 0.32
DRD1 P21728 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8968613 0.82 ITGB3 (0.34) HRH3LTA4HITGB3ITGA2BF2R
SCHEMBL500612 0.76 LTA4H (0.43) HRH3LTA4HOGFRL1CYP1A2MAPK1
SCHEMBL29264141 0.75 NPC1 (0.36) SMN1; SMN2
SCHEMBL652903 0.75 NPC1 (0.36) SMN1; SMN2
SCHEMBL652905 0.75 NPC1 (0.36) SMN1; SMN2
SCHEMBL652904 0.75 NPC1 (0.36) SMN1; SMN2
SCHEMBL14968754 0.73 ALDH1A1 (0.35) HRH3CYP1A2DRD2DRD1
SCHEMBL9489055 0.73 HRH3 (0.60) HRH3
SCHEMBL12809484 0.73 HRH3 (0.60) HRH3
SCHEMBL15779084 0.69 LTA4H (0.41) HRH3LTA4HOPRD1NR1H4OGFRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107686852-B Preparation method of moxifloxacin intermediate compound 上海朴颐化学科技有限公司 2022-08-02 CN disclosed