Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841917 | 0.86 | LMNA (0.39) | LMNATDP1POLB | |
| SCHEMBL27893570 | 0.85 | LMNA (0.37) | LMNATDP1DRD2DRD3POLB | |
| SCHEMBL4039302 | 0.79 | LMNA (0.41) | LMNATDP1POLB | |
| SCHEMBL28801372 | 0.76 | LMNA (0.42) | LMNAPOLB | |
| SCHEMBL4842879 | 0.70 | LMNA (0.40) | LMNATDP1POLB | |
| SCHEMBL4562101 | 0.65 | KMT2A (0.42) | LMNATDP1POLB | |
| SCHEMBL4035782 | 0.65 | PKM (0.39) | LMNAPOLB | |
| SCHEMBL4842372 | 0.63 | LMNA (0.48) | LMNAPOLB | |
| SCHEMBL4030551 | 0.63 | LMNA (0.40) | LMNATDP1POLB | |
| SCHEMBL18041160 | 0.61 | TGM2 (0.47) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746214-A | Novel indoline compounds | FOURNIER LAB SA | 2012-10-24 | — | — | CN | disclosed |