Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28946338 | 0.83 | NOTUM (0.43) | ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL28800159 | 0.83 | KMT2A (0.56) | KMT2AMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL28800153 | 0.78 | MAPT (0.46) | KMT2AMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL15004863 | 0.76 | ALDH1A1 (0.71) | KMT2AMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL28800120 | 0.74 | POLB (0.52) | KMT2AMAPK1ALDH1A1HPGDHTT | |
| SCHEMBL16033357 | 0.73 | GABRA2 (0.49) | KMT2AMAPK1ALDH1A1KDM4EGABRA2 | |
| SCHEMBL408365 | 0.73 | DGAT1 (0.59) | KMT2AMAPK1ALDH1A1KDM4EGABRA2 | |
| SCHEMBL28800137 | 0.73 | POLB (0.52) | KMT2AMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL11561773 | 0.72 | KMT2A (0.53) | KMT2AMAPK1ALDH1A1KDM4EGABRA2 | |
| SCHEMBL28800129 | 0.72 | HTT (0.51) | KMT2AMAPK1ALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790176-A | Imidazole compound and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-26 | — | — | CN | disclosed |