Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800120 | 0.86 | POLB (0.52) | MAPTKMT2AHPGDHTTALDH1A1 | |
| SCHEMBL28800137 | 0.85 | POLB (0.52) | MAPTKDM4EMEN1KMT2AHPGD | |
| SCHEMBL28800129 | 0.85 | HTT (0.51) | MAPTKMT2AHPGDHTTALDH1A1 | |
| SCHEMBL28800162 | 0.84 | HPGD (0.50) | MAPTKDM4EHSP90AA1KMT2AHPGD | |
| SCHEMBL28800159 | 0.83 | KMT2A (0.56) | MAPTKDM4EKMT2AHPGDHTT | |
| SCHEMBL15005072 | 0.82 | MAPT (0.66) | MAPTKDM4EMEN1HSP90AA1CRHBP | |
| SCHEMBL28800135 | 0.82 | GRM5 (0.46) | MAPTMAPK1GRM5SMN1; SMN2 | |
| SCHEMBL27769609 | 0.82 | ALDH1A1 (0.66) | MAPTKDM4EMEN1KMT2AHPGD | |
| SCHEMBL28800115 | 0.78 | KMT2A (0.51) | MAPTKDM4EKMT2AHPGDHTT | |
| SCHEMBL25044788 | 0.77 | ADORA1 (0.47) | MAPTKDM4EMEN1HSP90AA1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790176-A | Imidazole compound and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-26 | — | — | CN | disclosed |