Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800129 | 0.90 | HTT (0.51) | HPGDHTTMAPTALDH1A1GAA | |
| SCHEMBL28800137 | 0.87 | POLB (0.52) | HPGDHTTMAPTALDH1A1GAA | |
| SCHEMBL28800159 | 0.87 | KMT2A (0.56) | HPGDHTTMAPTALDH1A1GAA | |
| SCHEMBL27769609 | 0.87 | ALDH1A1 (0.66) | HPGDHTTMAPTALDH1A1GAA | |
| SCHEMBL28800122 | 0.85 | RAB9A (0.48) | MAPTALDH1A1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL28800153 | 0.84 | MAPT (0.46) | HPGDHTTMAPTALDH1A1GAA | |
| SCHEMBL28800120 | 0.83 | POLB (0.52) | HPGDHTTMAPTALDH1A1GAA | |
| SCHEMBL15004788 | 0.80 | ALDH1A1 (0.73) | HPGDHTTMAPTALDH1A1GAA | |
| SCHEMBL28800116 | 0.79 | GABRA2 (0.52) | HPGDHTTMAPTALDH1A1GAA | |
| SCHEMBL29800446 | 0.79 | GABRA2 (0.52) | HPGDHTTMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790176-A | Imidazole compound and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-26 | — | — | CN | disclosed |