Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800129 | 0.88 | HTT (0.51) | ALDH1A1MAPTGAAMAPK1ALOX15 | |
| SCHEMBL28800162 | 0.87 | HPGD (0.50) | ALDH1A1MAPTGAAMAPK1ALOX15 | |
| SCHEMBL28800137 | 0.86 | POLB (0.52) | ALDH1A1MAPTGAAMAPK1HPGD | |
| SCHEMBL28800159 | 0.86 | KMT2A (0.56) | ALDH1A1MAPTGAAMAPK1HPGD | |
| SCHEMBL24556944 | 0.86 | ALDH1A1 (0.62) | ALDH1A1MAPTGAAMAPK1ALOX15 | |
| SCHEMBL28800116 | 0.85 | GABRA2 (0.52) | ALDH1A1MAPTGAAMAPK1ALOX15 | |
| SCHEMBL29800446 | 0.85 | GABRA2 (0.52) | ALDH1A1MAPTGAAMAPK1ALOX15 | |
| SCHEMBL29800240 | 0.84 | ALOX15 (0.50) | ALDH1A1MAPTGAAMAPK1ALOX15 | |
| SCHEMBL28800117 | 0.84 | ALOX15 (0.50) | ALDH1A1MAPTGAAMAPK1ALOX15 | |
| SCHEMBL28800153 | 0.82 | MAPT (0.46) | ALDH1A1MAPTGAAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101492424-A | Actinochemical synthesis of 1H-imidazole-5-carboxylic acid ester compounds | UNIV BEIJING TECHNOLOGY (CN) | 2009-07-29 | — | — | CN | disclosed |