Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27886878 | 0.81 | CHRM3 (0.56) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4391727 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4EMCHR1TDP1MAPK1 | |
| SCHEMBL4812050 | 0.80 | MCHR1 (0.50) | ALDH1A1KDM4EMCHR1TDP1MAPK1 | |
| SCHEMBL6270367 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EMCHR1TDP1TSHR | |
| Zamifenacin SCHEMBL8938193 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4EMCHR1TDP1MAPK1 | |
| Zamifenacin SCHEMBL3227612 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4EMCHR1TDP1MAPK1 | |
| Zamifenacin SCHEMBL311829 | 0.78 | ADRA1D (0.46) | ALDH1A1KDM4EMCHR1TDP1TSHR | |
| Zamifenacin SCHEMBL1933745 | 0.78 | ADRA1D (0.46) | ALDH1A1KDM4EMCHR1TDP1TSHR | |
| SCHEMBL28800490 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4EMCHR1TDP1MAPK1 | |
| Zamifenacin SCHEMBL4603503 | 0.77 | ADRA1D (0.46) | ALDH1A1KDM4EMCHR1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101928280-B | Pepperphentonamine derivative containing naphthalene rings | GUANGZHOU ZHONGWEI BIOTECHNOLOGY CO LTD | 2012-09-12 | — | — | CN | disclosed |