Zamifenacin

Zamifenacin

SCHEMBL311829

c1ccc(C(O[C@@H]2CCCN(CCc3ccc4c(c3)OCO4)C2)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 3/20 0.46
ADRA1A P35348 3/20 0.46
ADRA1B P35368 3/20 0.46
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
MCHR1 Q99705 1/20 0.43
NOS2 P35228 2/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
OPRM1 P35372 1/20 0.42
OPRD1 P41143 1/20 0.42
OPRK1 P41145 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zamifenacin SCHEMBL1933745 1.00 ADRA1D (0.46) ADRA1DADRA1AADRA1BKDM4EMEN1
Zamifenacin SCHEMBL4603503 0.99 ADRA1D (0.46) ADRA1DADRA1AADRA1BKDM4EMEN1
Zamifenacin SCHEMBL8938193 0.93 KDM4E (0.45) ADRA1DADRA1AADRA1BKDM4EMEN1
Zamifenacin SCHEMBL3227612 0.93 KDM4E (0.45) ADRA1DADRA1AADRA1BKDM4EMEN1
Zamifenacin SCHEMBL13957310 0.92 SLC6A2 (0.41) ADRA1DADRA1AADRA1BMAPK1MCHR1
Zamifenacin SCHEMBL13957195 0.92 SLC6A2 (0.41) ADRA1DADRA1AADRA1BMAPK1MCHR1
Zamifenacin SCHEMBL13957205 0.91 NOS2 (0.42) ADRA1DADRA1AADRA1BMEN1MAPK1
SCHEMBL8938462 0.90 KCNH2 (0.44) ADRA1DADRA1AADRA1BKDM4ENOS2
Zamifenacin SCHEMBL13957196 0.90 ADRA1D (0.45) ADRA1DADRA1AADRA1BKDM4EMEN1
Zamifenacin SCHEMBL13957218 0.90 NOS2 (0.41) ADRA1DADRA1AADRA1BKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
EP-4581166-A1 CHRM3 AS A MARKER AND TARGET FOR COLON CANCER THERAPY Indivumed GmbH (DE) 2025-07-09 EP claimed
US-20250073237-A1 METHODS OF TREATING OR PREVENTING PRETERM LABOR VISCO ANTHONY G (US) 2025-03-06 US claimed
WO-2024047001-A1 CHRM3 AS A MARKER AND TARGET FOR COLON CANCER THERAPY INDIVUMED GMBH (DE) 2024-03-07 WO claimed
US-20240066018-A1 CHRM3 AS A MARKER AND TARGET FOR CANCER THERAPY INDIVUMED GMBH (DE) 2024-02-29 US claimed
EP-4178948-A2 FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF Universidade de Santiago de Compostela (ES) 2023-05-17 EP claimed
US-20220160711-A1 METHODS OF TREATING OR PREVENTING PRETERM LABOR VISCO ANTHONY G (US) 2022-05-26 US claimed
US-11285141-B2 Composition and methods for the treatment of myopia Seinda Pharmaceutical Guangzhou Corporation (CN) 2022-03-29 US claimed
WO-2022023496-A2 FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2022-02-03 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060241134-A1 Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility ALTANA PHARMA GA (DE) 2006-10-26 US claimed
EP-1273301-B1 Pharmaceutical preparations based on active ingredients susceptible to illicit administration ALTERGON SA (CH) 2006-09-06 EP claimed
EP-1644043-A1 PHARMACEUTICAL COMBINATIONS OF A PROTON PUMP INHIBITOR AND A COMPOUND WHICH MODIFIES GASTROINTESTINAL MOTILITY ALTANA Pharma AG (DE) 2006-04-12 EP claimed
US-20050107349-A1 Method for the treatment or prevention of respiratory disorders with a cyclooxygenase-2 inhibitor in combination with a muscarinic receptor antagonist and compositions therewith PHARMACIA CORPORATION (US) 2005-05-19 US claimed
WO-2004105795-A1 PHARMACEUTICAL COMBINATIONS OF A PROTON PUMP INHIBITOR AND A COMPOUND WHICH MODIFIES GASTROINTESTINAL MOTILITY ALTANA PHARMA AG (DE) 2004-12-09 WO claimed
EP-1273301-A2 Pharmaceutical preparations based on active ingredients susceptible to illicit administration ALTERGON S.A. (CH) 2003-01-08 EP claimed
EP-0350309-B1 PIPERIDINE DERIVATIVES Pfizer Limited (GB) 1992-11-11 EP claimed
US-5089505-A Anticholinergic agents PFIZER INC. (US) 1992-02-18 US claimed
EP-0350309-A1 Piperidine derivatives Pfizer Limited (GB) 1990-01-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050107349-A1 Method for the treatment or prevention of respiratory disorders with a cyclooxygenase-2 inhibitor in combination with a muscarinic receptor antagonist and compositions therewith CHRM3, CYSLTR2, CHRM2 ADRA1D 190/4885ADRA1A 224/4885ADRA1B 160/4885
US-20220160711-A1 METHODS OF TREATING OR PREVENTING PRETERM LABOR CHRM3, ADRB3, CHRNA3 ADRA1D 59/4885ADRA1A 42/4885ADRA1B 49/4885
US-20250073237-A1 METHODS OF TREATING OR PREVENTING PRETERM LABOR CHRM3, ADRB3, CHRNA3 ADRA1D 59/4885ADRA1A 42/4885ADRA1B 49/4885
US-11285141-B2 Composition and methods for the treatment of myopia CHRM3, CHRM2, MYOC ADRA1D 99/4885ADRA1A 74/4885ADRA1B 63/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.