Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28593231 | 0.85 | CYP1A2 (0.52) | L3MBTL1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL1192529 | 0.84 | CDC7 (0.61) | L3MBTL1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL18055899 | 0.84 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL3497038 | 0.82 | SMN1; SMN2 (0.51) | L3MBTL1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7455571 | 0.82 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL14059455 | 0.81 | TBK1 (0.50) | L3MBTL1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL1726531 | 0.79 | TRPM8 (0.71) | L3MBTL1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL28816710 | 0.78 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL496802 | 0.76 | ALDH1A1 (1.00) | L3MBTL1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL5195843 | 0.75 | PTGDR2 (0.52) | ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947292-A | nitrogen-containing heteroaryl compounds | HOFFMANN LA ROCHE | 2013-02-27 | — | — | CN | disclosed |