Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 4/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684000 | 0.80 | KDR (0.38) | POLBCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18175977 | 0.80 | KDR (0.38) | POLBCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL862853 | 0.80 | MAPKAPK2 (0.39) | CYP1A2CYP3A4CYP2C9CYP2C19KDR | |
| SCHEMBL1621164 | 0.78 | ALDH1A1 (0.38) | CYP1A2CYP3A4CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL862858 | 0.78 | ALDH1A1 (0.38) | CYP1A2CYP3A4CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL27895495 | 0.75 | DPP4 (0.40) | POLBCYP1A2CYP2C9CYP2C19KDR | |
| SCHEMBL460319 | 0.69 | HTT (0.48) | POLBCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23924759 | 0.69 | EGFR (0.46) | POLBCYP1A2KDRALDH1A1KDM4E | |
| SCHEMBL1442559 | 0.68 | PGK1 (0.51) | ALDH1A1KDM4ESMN1; SMN2STK17A | |
| SCHEMBL14300707 | 0.68 | KMT2A (0.40) | POLBCYP2C9ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103025735-A | Process for the preparation of 5-substituted-8-alkoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-amines | DOW AGROSCIENCES LLC | 2013-04-03 | — | — | CN | disclosed |